Reception: This study was conducted last month and has not been published in a journal or has been peer-reviewed, but external experts said it was a major development. “There is no doubt that this is a very important breakthrough,” said Darren K Griffin, professor of genetics at the University of Kent in the United Kingdom. “The research team carefully used a brain-dead patient to attach the kidney outside the body and monitor it closely for a limited time. So there is still a long way to go and there are many discoveries,” he added.
“This is a huge breakthrough. Dr. Dorry Segev, professor of transplant surgery at the Johns Hopkins School of Medicine who was not involved in this study, told the New York Times. However, he added: “We need to learn more about the life span of organs. “
background: In recent years, research has increasingly used pigs as the most promising way to help solve the problem of organ shortages, but it faces many obstacles. The most prominent fact is that the sugar in pig cells can trigger positive rejection in humans.
Researchers solved this problem by genetically modifying donor pigs to knock out the genes encoding sugar molecules that cause rejection. This pig was genetically engineered by Revivercor, one of several biotech companies dedicated to the development of pig organ transplantation into the human body.
Grand Prize: More kidneys are urgently needed for transplantation. According to the National Kidney Foundation, there are currently more than 100,000 people in the United States waiting for kidney transplants, and 13 people die from kidney transplants every day. If the methods tested at New York University Langone can last longer, genetically modified pigs can provide these people with a vital lifeline.
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